Products
Distributor of medac diagnostics products
Brochures
Product specialist: Svend Birkelund
E-mail: loke@loke.dk
Phone: +45 4096 1916
Antigens
Recombinant proteins (his-tag)
Primer design, PCR, cloning, control sequencing, expression and purification of 5 mg protein, 20,000 €
Cultivation of recombinant E. coli and purification of his-tag protein (350 €/mg, minimum order 25 mg)
Antibodies
Production and purification of monoclonal antibodies (MAb) from customer clone:
Purified IgG 350 €/mg (minimum order 50 mg)
Development project of MAb to peptide
Peptide syntheses of antigens, immunization of mice, test for immune response, fusion, selection of positive clones, test sample, 35.000 €
Referances
Axelsen TV, Holm A, Birkelund S, Christiansen G, Ploug M, Holm IE. Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody. Mol Immunol. 2009; 46: 2267-73
Hjelholt A, Christiansen G, Johannesson TG, Ingerslev HJ, Birkelund S. Tubal factor infertility is associated with antibodies against Chlamydia trachomatis heat shock protein 60 (HSP60) but not human HSP60. Hum Reprod. 2011 Aug;26(8):2069-76.
Axelsen TV, Holm A, Christiansen G, Birkelund S. Identification of the shortest Aβ-peptide generating highly specific antibodies against the C-terminal end of amyloid-β42. Vaccine. 2011 Apr 12;29(17):3260-9.
Chiliveru S, Birkelund S, Paludan SR. Induction of interferon-stimulated genes by Chlamydia pneumoniae in fibroblasts is mediated by intracellular nucleotide-sensing receptors. PLoS One. 2010 Apr 6;5(4):e10005.
Hobolt-Pedersen AS, Christiansen G, Timmerman E, Gevaert K, Birkelund S. Identification of Chlamydia trachomatis CT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus. FEMS Immunol Med Microbiol. 2009 Oct;57(1):46-58.
Drasbek M, Christiansen G, Drasbek KR, Holm A, Birkelund S. Interaction between the P1 protein of Mycoplasma pneumoniae and receptors on HEp-2 cells. Microbiology. 2007 Nov;153(Pt 11):3791-9.
Juul N, Timmerman E, Gevaert K, Christiansen G, Birkelund S. Proteolytic cleavage of the Chlamydia pneumoniae major outer membrane protein in the absence of Pmp10. Proteomics. 2007 Dec;7(24):4477-87.
Svenstrup HF, Jensen JS, Gevaert K, Birkelund S, Christiansen G. Identification and characterization of immunogenic proteins of Mycoplasma genitalium. Clin Vaccine Immunol. 2006 Aug;13(8):913-22.
Products developed for medac
Chlamydia
Chlamydia trachomatis
C. trachomatis-IgA- and IgG-pELISA (medac)
C. trachomatis cHSP60-IgG-ELISA (medac)
Chlamydia pneumoniae
C. pneumoniae-IgG-, IgA- and IgM-sELISA (medac)
Bacteria
Mycoplasma pneumoniae-IgG, IgA- and IgM-ELISA (medac)
Borrelia-IgG, IgM ELISA medac
Virus
Parvovirus B19-IgG -IgM